Concordance for curve type in idiopathic scoliosis among family members

Concordance for curve type in idiopathic scoliosis among family members

OBJECTIVE To evaluate the concordance for the curve pattern, side and levels of the superior apical vertebrae, apex and inferior apical vertebrae of curves in patients and their relatives with idiopathic scoliosis. METHODS Concordance according to the Lenke classification for curve pattern, side and levels of the superior apical vertebrae, apex and inferior apical vertebrae were evaluated com...

Genetic aspects of adolescent idiopathic scoliosis in a family with multiple affected members: a research article

BACKGROUND The etiology of idiopathic scoliosis remains unknown and different factors have been suggested as causal. Hereditary factors can also determine the etiology of the disease; however, the pattern of inheritance remains unknown. Autosomal dominant, X-linked and multifactorial patterns of inheritances have been reported. Other studies have suggested possible chromosome regions related to...

Johnson Assessment of curve progression in idiopathic scoliosis

A major concern of orthopedic surgeons in managing children with idiopathic scoliosis with a minor curvature is identifying how many and which curves will progress to severe deformities requiring treatment [1, 3–12, 14, 15]. Accurate identification of curves destined to progress requires a clear understanding of the natural history of idiopathic scoliosis. In this regard, school screening has b...

University of Groningen Prediction of Curve Progression in Idiopathic Scoliosis

Concordance of survival in family members with prostate cancer.

PURPOSE Several earlier studies have assessed survival in prostate cancer based on familial risk of this disease. As a novel concept, we posit that factors governing survival in prostate cancer are likely to be different from those governing risk of prostate cancer. To prove this, we searched for familial clustering of survival (ie, concordance of survival among family members). PATIENTS AND ...